欧文原著 - 当研究室の2008年の業績です。
- Umeda A, Kawasaki K, Abe T, Watanabe M, Ishizaka A, Okada Y. Hyperventilation and finger exercise increase venous-arterial Pco2 and pH differences. The American Journal of Emergency Medicine 26(9): 975-980, 2008.
- Watanabe H, Soejima K, Yasuda H, Kawada I, Nakachi I, Yoda S, Naoki K, Ishizaka A. Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells. Cancer Cell Int. 2008 Nov 3;8:15.
- Kawada I, Soejima K, Watanabe H, Nakachi I, Yasuda H, Naoki K, Kawamura M, Eguchi K, Kobayashi K, Ishizaka A. An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients. J Thorac Oncol. 2008 Oct;3(10):1096-103.
- Ishii M, Hogaboam CM, Joshi A, Ito T, Fong DJ, Kunkel SL. CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling. Eur J Immunol. 2008 Aug;38(8):2290-302.
- Yamada W, Tasaka S, Koh H, Shimizu M, Ogawa Y, Hasegawa N, Miyasho T, Yamaguchi K, Ishizaka A. Role of Toll-like receptor 4 in acute neutrophilic lung inflammation induced by intratracheal bacterial products in mice. J Inflamm Res. 1: 1-10, 2008.
- Director's Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma, Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Giordano TJ, Misek DE, Chang AC, Zhu CQ, Strumpf D, Hanash S, Shepherd FA, Ding K, Seymour L, Naoki K, Pennell N, Weir B, Verhaak R, Ladd-Acosta C, Golub T, Gruidl M, Sharma A, Szoke J, Zakowski M, Rusch V, Kris M, Viale A, Motoi N, Travis W, Conley B, Seshan VE, Meyerson M, Kuick R, Dobbin KK, Lively T, Jacobson JW, Beer DG. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med. 2008 Aug;14(8):822-7.
- Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X, Naoki K, Okamoto I, Nakagawa K, Yeap BY, Meyerson M, Wong KK, Richards WG, Sugarbaker DJ, Johnson BE, Jinne PA. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. Br J Cancer. 2008 Jul 22;99(2):245-52.
- Cavassani KA, Ishii M, Wen H, Schaller MA, Lincoln PM, Lukacs NW, Hogaboam
CM, Kunkel SL. TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory
events. J Exp Med. 2008 Oct 27;205(11):2609-21. - Hagio T, Kishikawa K, Kawabata K, Tasaka S, Hashimoto S, Hasegawa N, Ishizaka A. Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters. Pulm Pharmacol Ther. 21: 884-891, 2008.
- Inoue K, Takano H, Koike E, Yanagisawa R, Sakurai M, Tasaka S, Ishizaka A, Shimada A. Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice. Exp Biol Med. 233:1583-1590, 2008.
- Inoue K, Takano H, Kaewamatawong T, Shimada A, Suzuki J, Yanagisawa R, Tasaka S, Ishizaka A, Satoh M. Role of metallothionein in lung inflammation induced by ozone exposure in mice. Free Radic Biol Med. 45: 1714-1722, 2008.
- Tajima A, Kohno M, Watanabe M, Izumi Y, Tasaka S, Maruyama I, Miyasho T, Kobayashi K. Occult injury in the residual lung after pneumonectomy in mice. Interact Cardiovasc Thorac Surg. 7:1114-1120, 2008.
- Nishimura T, Hasegawa N, Watanabe M, Takebayashi T, Tasaka S, Ishizaka A.
Bronchoscopic microsampling to analyze the epithelial lining fluid of patients with pulmonary Mycobacterium avium complex disease.v Respiration. 2008;76(3):338-43. - Kipnis E, Hansen K, Sawa T, Moriyama K, Zurawel A, Ishizaka A, Wiener-Kronish J.
Proteomic analysis of undiluted lung epithelial lining fluid.
Chest. 2008 Aug;134(2):338-45. - Hashimoto S, Amaya F, Matsuyama H, Ueno H, Kikuchi S, Tanaka M, Watanabe Y, Ebina M, Ishizaka A, Tsukita S, Hashimoto S.
Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin.
Am J Physiol Lung Cell Mol Physiol. 2008 Oct;295(4):L566-74. - Takahashi S, Kuwabara K, Sawafuji M, Akiduki S, Ishizaka A.
F-18 FDG PET imaging in a patient with granulocyte colony stimulating factor producing pulmonary pleomorphic carcinoma.
Clin Nucl Med. 2008 Aug;33(8):555-7. No abstract available. - Zhang H, Tasaka S, Shiraishi Y, Fukunaga K, Yamada W, Seki H, Ogawa Y, Miyamoto K, Nakano Y, Hasegawa N, Miyasho T, Maruyama I, Ishizaka A.
Role of soluble receptor for advanced glycation end products on endotoxin-induced lung injury.
Am J Respir Crit Care Med. 2008 Aug 15;178(4):356-62. Epub 2008 Jun 5. - Oyamada Y, Murai M, Harada N, Ishizaka A, Okada Y.
Age-dependent involvement of ATP-sensitive potassium channel Kir6.2 in hypoxic ventilatory depression of mouse.
Respir Physiol Neurobiol. 2008 Jun 30;162(1):80-4 - Takahashi S, Nakamura H, Seki M, Shiraishi Y, Yamamoto M, Furuuchi M, Nakajima T, Tsujimura S, Shirahata T, Nakamura M, Minematsu N, Yamasaki M, Tateno H, Ishizaka A.
Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice.
Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L882-90. - Tasaka S, Amaya F, Hashimoto S, Ishizaka A.
Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome.
Antioxid Redox Signal. 2008 Apr;10(4):739-53. Review. - Kikuta H, Sakata C, Gamo R, Ishizaka A,Koga Y, Konno M, Ogasawara Y, Sawada H, Taguchi Y, Takahashi Y, Yasuda K, Ishiguro N, Hayashi A, Ishiko H, Kobayashi K.
Comparison of a lateral-flow immunochromatography assay with real-time reverse transcription-PCR for detection of human metapneumovirus.
J Clin Microbiol. 2008 Mar;46(3):928-32. Epub 2008 Jan 3. - Kikuchi E, Yamazaki K, Kikuchi J, Hasegawa N, Hashimoto S, Ishizaka A, Nishimura M.
Pharmacokinetics of clarithromycin in bronchial epithelial lining fluid.
Respirology. 2008 Mar;13(2):221-6. - Koh H, Tasaka S, Hasegawa N, Asano K, Kotani T, Morisaki H, Takeda J, Fujishima S, Matsuda T, Hashimoto S, Ishizaka A.
Vascular endothelial growth factor in epithelial lining fluid of
patients with acute respiratory distress syndrome.
Respirology. 2008 Mar;13(2):281-4. - van Zoelen MA, Ishizaka A, Wolthuis EK, Choi G, van der Poll T, Schultz MJ.
Pulmonary levels of high-mobility group box 1 during mecahical ventilation and bentilator-associated pneumonia.
Shock. 2008 Apr;29(4):441-445. - Hashimoto S, Okayama Y, Shime N, Kimura A, Funakoshi Y, Kawabata K, Ishizaka A, Amaya F.
Neutrophil elastase activity in acute lung injury and respiratory distress syndrome.
Respirology. 2008 Jun;13(4):581-4 - Minematsu N, Nakamura H, Furuuchi M, Nakajima T, Takahashi S, Tsujimura S, Tateno H, Ishizaka A.
Common functional polymorphisms in the cathepsin S promoter in Japanese subjects: Possible contribution to pulmonary emphysema.
Respirology. 2008 Jun;13(4):498-504. - Aoki T, Yamasawa F, Kawashiro T, Shibata T, Ishizaka A, Urano T, Okada Y.
Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung.
Respir Res. 2008 Apr 26;9(1):37. - Mizuta M, Nakajima H, Mizuta N, Kitamura Y, Nakajima Y, Hashimoto S, Matsuyama H, Shime N, Amaya F, Koh H, Ishizaka A, Magae J, Tanuma S and Hashimoto S.
Fas Ligand Released by Activated Monocytes Causes Apoptosis of Lung Epithelial Cells in Human Acute Lung Injury Model in Vitro.
Biol. Pharm. Bull. 2008:31(3):386-390. - Nishimura T, Hasegawa N, Mori M, Takebayashi T, Harada N, Higuchi K, Tasaka S, Ishizaka A.
Accuracy of an interferon- release assay to detect active pulmonary and extra-pulmonary tuberculosis.
The International Journal of Tuberculosis and Lung Disease. 2008 Mar: 12(3):269-274. - Shiraishi Y, Asano K, Niimi K, Fukunaga K, Wakaki M, Kagyo J, Takihara T, Ueda S, Nakajima T, Oguma T, Suzuki Y, Shiomi T, Sayama K, Kagawa S, Ikeda E, Hirai H, Nagata K, Nakamura M, Miyasho T, Ishizaka A. Cyclooxygenase-2/Prostaglandin D2/CRTH2 Pathway Mediates Double-Stranded RNA-Induced Enhancement of Allergic Airway Inflammation.
J Immunol. 2008 Jan 1;180(1):541-9 - Saito F, Tasaka S, Inoue KI, Miyamoto K, Nakano Y, Ogawa Y, Yamada W, Shiraishi Y, Hasegawa N, Fujishima S, Takano H, Ishizaka A.
Role of Interleukin-6 in Bleomycin-induced Lung Inflammatory Changes in Mice.
Am J Respir Cell Mol Biol. 2008 May;38(5):566-71 - Fujishima S, Morisaki H, Ishizaka A, Kotake Y, Miyaki M, Yoh K, Sekine K, Sasaki J, Tasaka S, Hasegawa N, Kawai Y, Takeda J, Aikawa N.
Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients.
Biomed Pharmacother. 2008 Jun;62(5):333-8