業績

2018年業績

欧文原著 - 当研究室の2018年の業績です。

  1. The eggs of Paragonimiasis westermani in bronchial lavage fluid.
    Masaki K, Asakura T, Nakachi I.
    QJM. 2018 Dec 28. doi: 10.1093/qjmed/hcy301.
  2. Neutrophil to lymphocyte ratio is a novel independent predictor of severe exacerbation in asthma patients.
    Mochimaru T, Ueda S, Suzuki Y, Asano K, Fukunaga K.
    Ann Allergy Asthma Immunol. 2018 Nov 30. pii: S1081-1206(18)31500-X. doi: 10.1016/j.anai.2018.11.029.
  3. Calorie restriction enhances adult mouse lung stem cells function and reverses several aging-induced changes.
    Hegab AE, Ozaki M, Meligy FY, Nishino M, Kagawa S, Ishii M, Betsuyaku T.
    J Tissue Eng Regen Med. 2018 Dec 18. doi: 10.1002/term.2792.
  4. First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti-interferon-gamma autoantibodies.
    Namkoong H, Asakura T, Ishii M, Yoda S, Masaki K, Sakagami T, Iwasaki E, Yamagishi Y, Kanai T, Betsuyaku T, Hasegawa N.
    New Microbes New Infect. 2018 Oct 19;27:4-6. doi: 10.1016/j.nmni.2018.10.001. eCollection 2019 Jan.
  5. Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease.
    Asakura T, Yamada Y, Suzuki S, Namkoong H, Okamori S, Kusumoto T, Niijima Y, Ozaki A, Hashimoto M, Yagi K, Kamata H, Funatsu Y, Ishii M, Jinzaki M, Betsuyaku T, Hasegawa N.
    Respir Med. 2018 Dec;145:66-72. doi: 10.1016/j.rmed.2018.10.023. Epub 2018 Oct 22.
  6. Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin-Induced Pulmonary Inflammation and Fibrosis.
    Ueda S, Fukunaga K, Takihara T, Shiraishi Y, Oguma T, Shiomi T, Suzuki Y, Ishii M, Sayama K, Kagawa S, Hirai H, Nagata K, Nakamura M, Miyasho T, Betsuyaku T, Asano K.
    Am J Respir Cell Mol Biol. 2018 Oct 16. doi: 10.1165/rcmb.2017-0397OC.
  7. High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects.
    Hegab AE, Ozaki M, Meligy FY, Kagawa S, Ishii M, Betsuyaku T.
    Stem Cell Res. 2018 Dec;33:25-35. doi: 10.1016/j.scr.2018.10.006. Epub 2018 Oct 4.
  8. Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease.
    Asakura T, Nakagawa T, Suzuki S, Namkoong H, Morimoto K, Ishii M, Kurashima A, Betsuyaku T, Ogawa K, Hasegawa N; Nontuberculous Mycobacteriosis Japan Research Consortium (NTM-JRC).
  9. A randomized trial of symptom-based management in Japanese patients with COPD.
    Betsuyaku T, Kato M, Fujimoto K, Kobayashi A, Hayamizu T, Hitosugi H, Hagan G, James MH, Jones PW.
    Int J Chron Obstruct Pulmon Dis. 2018 Aug 13;13:2409-2423. doi: 10.2147/COPD.S152723. eCollection 2018.
  10. Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: a case report.
    Kobayashi K, Asakura T, Ishii M, Ueda S, Irie H, Ozawa H, Saitoh K, Kurihara I, Itoh H, Betsuyaku T.
    BMC Pulm Med. 2018 Aug 22;18(1):142. doi: 10.1186/s12890-018-0710-9.
  11. Prognostic Understanding at Diagnosis and Associated Factors in Patients with Advanced Lung Cancer and Their Caregivers.
    Sato T, Soejima K, Fujisawa D, Takeuchi M, Arai D, Nakachi I, Naoki K, Kawada I, Yasuda H, Ishioka K, Nukaga S, Kobayashi K, Masaki K, Inoue T, Hikima K, Nakamura M, Ohgino K, Oyamada Y, Funatsu Y, Terashima T, Miyao N, Sayama K, Saito F, Sakamaki F, Betsuyaku T.
    Oncologist. 2018 Oct;23(10):1218-1229. doi: 10.1634/theoncologist.2017-0329. Epub 2018 Aug 17.
  12. Sphingosine 1-phosphate receptor modulator ONO-4641 stimulates CD11b+Gr-1+ cell expansion and inhibits lymphocyte infiltration in the lungs to ameliorate murine pulmonary emphysema.
    Asakura T, Ishii M, Namkoong H, Suzuki S, Kagawa S, Yagi K, Komiya T, Hashimoto T, Okamori S, Kamata H, Tasaka S, Kihara A, Hegab AE, Hasegawa N, Betsuyaku T.
    Mucosal Immunol. 2018 Nov;11(6):1606-1620. doi: 10.1038/s41385-018-0077-5. Epub 2018 Aug 16.
  13. The FGF2 aptamer inhibits the growth of FGF2-FGFR pathway driven lung cancer cells.
    Hamamoto J, Yasuda H, Nonaka Y, Fujiwara M, Nakamura Y, Soejima K, Betsuyaku T.
    Biochem Biophys Res Commun. 2018 Sep 10;503(3):1330-1334. doi: 10.1016/j.bbrc.2018.07.044. Epub 2018 Jul 11.
  14. Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease.
    Yagi K, Asakura T, Namkoong H, Suzuki S, Asami T, Okamori S, Kusumoto T, Funatsu Y, Kamata H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N.
    BMC Pulm Med. 2018 Jul 13;18(1):114. doi: 10.1186/s12890-018-0686-5.
  15. Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer.
    Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T.
    Onco Targets Ther. 2018 Jun 6;11:3335-3343. doi: 10.2147/OTT.S161745. eCollection 2018.
  16. Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital.
    Asakura T, Ishii M, Ishii K, Suzuki S, Namkoong H, Okamori S, Kamata H, Yagi K, Funatsu Y, Betsuyaku T, Hasegawa N.
    Int J Tuberc Lung Dis. 2018 Jun 1;22(6):695-703. doi: 10.5588/ijtld.17.0433.
  17. Perfusion Defect-Concordant Progression of Unilateral Refractory Pulmonary Mycobacterium avium Complex Disease.
    Asakura T, Yamada Y, Ishii M, Ebisudani T, Ueda S, Betsuyaku T, Hasegawa N.
    Am J Respir Crit Care Med. 2018 Sep 15;198(6):803-804. doi: 10.1164/rccm.201801-0173IM.
  18. Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study.
    Suzuki S, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Uwamino Y, Funatsu Y, Nakano Y, Nishimura T, Ishii M, Ebihara T, Betsuyaku T, Hasegawa N.
    Respir Med. 2018 May;138:1-6. doi: 10.1016/j.rmed.2018.03.013. Epub 2018 Mar 12.
  19. Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients.
    Sakurai K, Chubachi S, Irie H, Tsutsumi A, Kameyama N, Kamatani T, Koh H, Terashima T, Nakamura H, Asano K, Betsuyaku T.
    BMC Pulm Med. 2018 May 2;18(1):65. doi: 10.1186/s12890-018-0639-z.
  20. Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms.
    Hegab AE, Ozaki M, Kagawa S, Hamamoto J, Yasuda H, Naoki K, Soejima K, Yin Y, Kinoshita T, Yaguchi T, Kawakami Y, Ornitz DM, Betsuyaku T.
    Lung Cancer. 2018 May;119:25-35. doi: 10.1016/j.lungcan.2018.02.015. Epub 2018 Mar 2.
  21. Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.
    Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Hegab AE, Kamata H, Tasaka S, Atarashi K, Nakamoto N, Iwata S, Honda K, Kanai T, Hasegawa N, Koyasu S, Betsuyaku T.
    PLoS Pathog. 2018 Apr 5;14(4):e1006955. doi: 10.1371/journal.ppat.1006955. eCollection 2018 Apr.
  22. Secondary Brain Neoplasm after Stereotactic Radiosurgery in Patients with Metastatic Non-small Cell Lung Cancer.
    Nukaga S, Naoki K, Yasuda H, Kawada I, Ohara K, Soejima K, Betsuyaku T.
    Intern Med. 2018 Mar 9. doi: 10.2169/internalmedicine.0184-17. [Epub ahead of print]
  23. Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody.
    Kusumoto T, Okamori S, Masuzawa K, Asakura T, Nishina N, Chubachi S, Naoki K, Fukunaga K, Betsuyaku T.
    Intern Med. 2018 Feb 28. doi: 10.2169/internalmedicine.0303-17. [Epub ahead of print]
  24. Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer.
    Hirano T, Yasuda H, Hamamoto J, Nukaga S, Masuzawa K, Kawada I, Naoki K, Niimi T, Mimasu S, Sakagami H, Soejima K, Betsuyaku T.
    Mol Cancer Ther. 2018 Apr;17(4):740-750. doi: 10.1158/1535-7163.MCT-17-1033. Epub 2018 Feb 21.
  25. Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More Than Continuous Exposure.
    Kameyama N, Chubachi S, Hegab AE, Yasuda H, Kagawa S, Tsutsumi A, Fukunaga K, Shimoda M, Kanai Y, Soejima K, Betsuyaku T.
    Am J Respir Cell Mol Biol. 2018 Feb 14. doi: 10.1165/rcmb.2017-0375OC. [Epub ahead of print]
  26. Real-world Efficacy and Safety of Nivolumab for Advanced Non-Small-cell Lung Cancer: A Retrospective Multicenter Analysis.
    Kobayashi K, Nakachi I, Naoki K, Satomi R, Nakamura M, Inoue T, Tateno H, Sakamaki F, Sayama K, Terashima T, Koh H, Abe T, Nishino M, Arai D, Yasuda H, Kawada I, Soejima K, Betsuyaku T; Keio Lung Oncology Group (KLOG).
    Clin Lung Cancer. 2018 May;19(3):e349-e358. doi: 10.1016/j.cllc.2018.01.001. Epub 2018 Jan 5.
  27. Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice.
    Asami T, Ishii M, Namkoong H, Yagi K, Tasaka S, Asakura T, Suzuki S, Kamo T, Okamori S, Kamata H, Zhang H, Hegab AE, Hasegawa N, Betsuyaku T.
    Cytotherapy. 2018 Mar;20(3):302-313. doi: 10.1016/j.jcyt.2018.01.003. Epub 2018 Feb 12.
  28. Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema.
    Sasaki M, Chubachi S, Kameyama N, Sato M, Haraguchi M, Miyazaki M, Takahashi S, Nakano T, Kuroda Y, Betsuyaku T, Matsuo K.
    PLoS One. 2018 Jan 30;13(1):e0191611. doi: 10.1371/journal.pone.0191611. eCollection 2018.
  29. Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease.
    Shirahata T, Nakamura H, Nakajima T, Nakamura M, Chubachi S, Yoshida S, Tsuduki K, Mashimo S, Takahashi S, Minematsu N, Tateno H, Asano K, Fujishima S, Betsuyaku T.
    Biomarkers. 2018 Feb 12:1-8. doi: 10.1080/1354750X.2018.1434682. [Epub ahead of print]
  30. Anti-aminoacyl tRNA Synthetase Antibody-Positive Clinically Amyopathic Dermatomyositis.
    Ebisudani T, Asakura T, Ueda S, Ishii M, Betsuyaku T.
    QJM. 2018 Jan 15. doi: 10.1093/qjmed/hcy008. [Epub ahead of print] No abstract available.
  31. Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: a case report with microbiological analysis.
    Okamori S, Asakura T, Nishimura T, Tamizu E, Ishii M, Yoshida M, Fukano H, Hayashi Y, Fujita M, Hoshino Y, Betsuyaku T, Hasegawa N.
    BMC Infect Dis. 2018 Jan 2;18(1):1. doi: 10.1186/s12879-017-2892-9.
  32. Recurrence of allergic bronchopulmonary aspergillosis after adjunctive surgery for aspergilloma: a case report with long-term follow-up.
    Horiuchi K, Asakura T, Hasegawa N, Saito F.
    BMC Pulm Med. 2018 Dec 4;18(1):185. doi: 10.1186/s12890-018-0743-0.
  33. Lung cancer masquerading as fungus-associated mucoid impaction.
    Horiuchi K, Asakura T, Sakaguchi S, Saito F.
    BMJ Case Rep. 2018 Dec 31;11(1):e227470. doi: 10.1136/bcr-2018-227470.

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